Annual reports on fermentation processes Volume 1 by D. Perlman, George T. Tsao

By D. Perlman, George T. Tsao

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24 R. P. ELANDER E T AL. virus (PBC) associated with P. chrysogenum increases in titer following exposure of infected cells to either UV radiation or proflavin (262). Of particular interest is a report of direct correlation of the PBV titer with the yield of penicillin. (263). Little information is known on the genetic basis of penicillin production in P. chrysogenum, and it has been suggested that the genetic basis for the partial synthesis of such secondary metabolites in fungi may involve viral determinants (264,265).

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